The latest news about the CMCiB. For more news of research at the IGTP, please see our main website.
Mesenchymal stem cells reveal mechanisms of action in regulatory B cells independent of interleukin-10 useful for their identification and monitoring
Researchers from the REMAR-IVECAT ("Kidney Related Diseases Research" and "Innovation in VEsicles and Cells for Application in Therapy") group, from the Germans Trias i Pujol Research Institute (IGTP), identify molecular pathways in regulatory B cells that are essential for their therapeutic applications. In the article that has been recently published in Frontiers in Immunology, the use of mesenchymal stem cells has allowed distinguishing the molecules that are essential to monitoring regulatory B cells in kidney transplants.
Bioimplants with extra-cellular vesicles from stem cells can improve cardiac function after an acute myocardial heart attack
Researchers from the ICREC Group (Cardiac Insufficiency and Regeneration) in cardiovascular diseases at the Germans Trias i Pujol Research Institute (IGTP) continue to work on therapeutic technologies to repair cardiac tissue after a heart attack. In an article published in Theranostics, they present a study of extracellular vesicles from mesenchymal stem cells combined with tissue engineering as a therapy to repair the heart after a heart attack. They have carried out the study on a porcine heart attack model at the Centre for Comparative Medicine and Bioimage (CMCiB) at the IGTP.
Time is Brain, Spin-off company from the IGTP, closes its financing round in little more than an hour
The seed-funding round for the IGTP Spin-off Time is Brain has reached its financing objective in record time almost as soon as it opened. The company opened the round on the platform Capital Cell and has not only reached the goal of 640,000, but has passed it and received 800,000, the figure the spin-off had set as a maximum.
Mireia Ramos Rodríguez is awarded the prize for the Best Research Paper by a Predoctoral Student by the Catalan Institute of Health
Mireia Ramos Rodríguez is a bioinformatics post-doctoral researcher; she focusses on defining the changes in cis-regulatory elements that can lead to the development of disease and programming to provide tools for other researchers to carry out their analyses. She has been awarded the Prize for Best Research Paper in Health by a Predoctoral Researcher for her article published in Nature Genetics.
The study focusses on understanding the mechanisms that keep the infection latent without the infected person developing the disease. 90% of people infected never develop the active disease, understanding this mechanism so that we can identify them is key to eradicating tuberculosis. The research has been carried out in virtual lungs, developed by computational modelling techniques. These are the first results to be published by the 3Rs Programme at the Centre for Comparative Medicine and Bioimage (CMCiB) which aims to minimize the use of animals in pre-clinical research.